Antimalarial Drugs

Product Details:

Uses

Treatment of slide-confirmed severe falciparum malaria in areas where there is evidence that quinine is ineffective. Radical cure should then be effected with a full dose of an effective oral antimalarial such as mefloquine.

Dosage and administration

Adults and children over 6 months: 3.2 mg/kg as a loading dose by intramuscular injection, followed by 1.6 mg/kg daily until the patient is able to tolerate oral medication or for a maximum of 7 days.

Precautions

Artemether should be used for the treatment of severe falciparum malaria only where there is evidence that the antimalarial efficacy of quinine is declining.

For children, since the injected volumes will be small, it is advisable to use a 1-ml syringe to ensure that the correct dose is given.

Use in pregnancy

Little experience has been gained with the use of this drug in pregnancy but it should not be withheld if it is considered life-saving to the mother.

Adverse effects

Neurotoxicity has been observed in animal studies but not in humans.

Cardiotoxicity has been observed following administration of high doses of artemether.

Storage

The oily preparation should be stored in tightly closed containers, protected from light.

Additional Information:

• Pay Mode Terms: L/C (Letter of Credit),T/T (Bank Transfer)
• Port of Dispatch: Any Port in india

Product Details:

Brand Names Tiotem

Generic Name artemether/lumefantrine (ar-TEM-e-ther/LOO-me-FAN-treen)

Tiotem is used for Treating certain types of malaria in adults and children who weigh at least 11 pounds (5 kg). It may also be used for other conditions as determined by your doctor.

Tiotem is an antimalarial agent.

How to use Tiotem Use Tiotem as directed by your doctor. Check the label on the medicine for exact dosing instructions.

This product is available in the following dosage forms

• An extra patient leaflet is available with Tiotem. Talk to your pharmacist if you have questions about this information.
• Take Tiotem by mouth with food.
• If you are unable to swallow the tablet, Tiotem may be crushed and mixed with a small amount of water (1 or 2 teaspoons) in a clean container. Swallow the mixture immediately; then rinse the container with more water and swallow to be sure you receive the entire dose. Follow with food or drink (eg, milk, formula, pudding, broth, porridge). Do not store the mixture for future use.
• Do not eat grapefruit or drink grapefruit juice while you use Tiotem.
• If you vomit within 1 hour after taking Tiotem, take another dose. If you vomit the repeat dose, contact your doctor.
• Ask your health care provider any questions you may have about how to use Tiotem

Proper storage of Tiotem Store Tiotem at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Tiotem out of the reach of children and away from pets.

Additional Information:

• Pay Mode Terms: L/C (Letter of Credit),T/T (Bank Transfer)
• Port of Dispatch: Any Port in india

Product Details:

DESCRIPTION:

Artemether & Lumefantrine tablets is a fixed-dose combination tablet of artemether and lumefantrine. Artemether is a methyl ether derivative of dihydroartemisinin, derived from artemisinin. Lumefantrine is a racemic 2, 4, 7, 9-substituted fluorine derivative that conforms structurally, physicochemically and in mode of action to the arylamino alcohol group of antimalarials that includes quinine and mefloquine.

COMPOSITION:

Each uncoated tablet contains:-

Artemether 20 mg

Lumefantrine 120 mg

Excipients q.s

INDICATIONS:

Artemether & Lumefantrine tablets are indicated for treatment of acute, uncomplicated malaria infections due to Plasmodium falciparum in patients of 5 kg bodyweight and above. Artemether & Lumefantrine tablets have been shown to be effective in geographical regions where resistance to chloroquine has been reported.

Limitations of Use:

Artemether & Lumefantrine tablets are not approved for patients with severe or complicated P. falciparum malaria.

 

CONTRAINDICATIONS:

Artemether & Lumefantrine tablets are contraindicated in persons with a history of hypersensitivity associated with the use of artemether, lumefantrine, or to any of the excipients of Artemether & Lumefantrine tablets.

 

STORAGE:Store in an airtight container, protected from light.

PRESENTATION: 4X6 Tablets in one blister in a monopack.

Additional Information:

• Production Capacity: any port in india

Product Details:

DESCRIPTION:

Artemether & Lumefantrine tablets is a fixed-dose combination tablet of artemether and lumefantrine. Artemether is a methyl ether derivative of dihydroartemisinin, derived from artemisinin. Lumefantrine is a racemic 2, 4, 7, 9-substituted fluorine derivative that conforms structurally, physicochemically and in mode of action to the arylamino alcohol group of antimalarials that includes quinine and mefloquine.

COMPOSITION:

Each un coated tablet contains:-

Artemether 40 mg

Lumefantrine 240 mg

Excipients q.s

INDICATIONS:

Artemether & Lumefantrine tabletsare indicated for treatment of acute, uncomplicated malaria infections due to Plasmodium falciparum in patients of 5 kg bodyweight and above. Artemether & Lumefantrine tablets have been shown to be effective in geographical regions where resistance to chloroquine has been reported.

Limitations of Use:

Artemether & Lumefantrine tabletsare not approved for patients with severe or complicated P. falciparum malaria.

 

CONTRAINDICATIONS:

Artemether & Lumefantrine tabletsare contraindicated in persons with a history of hypersensitivity associated with the use of artemether, lumefantrine, or to any of the excipients of Artemether & Lumefantrine tablets.

 

STORAGE:Store in an airtight container, protected from light.

PRESENTATION: 2x6 Tablets in one blister in a monopack.

Additional Information:

• Production Capacity: any port in india

Product Details:

DESCRIPTION:

Artemether & Lumefantrine tablets is a fixed-dose combination tablet of artemether and lumefantrine. Artemether is a methyl ether derivative of dihydroartemisinin, derived from artemisinin. Lumefantrine is a racemic 2, 4, 7, 9-substituted fluorine derivative that conforms structurally, physicochemically and in mode of action to the arylamino alcohol group of antimalarials that includes quinine and mefloquine.

COMPOSITION:

Each un coated tablet contains:-

Artemether              80 mg

Lumefantrine           480 mg

Excipients                q.s 

 

INDICATIONS:

Artemether & Lumefantrine tablets are indicated for treatment of acute, uncomplicated malaria infections due to Plasmodium falciparum in patients of 5 kg bodyweight and above. Artemether & Lumefantrine tablets have been shown to be effective in geographical regions where resistance to chloroquine has been reported.

Limitations of Use:

Artemether & Lumefantrine tablets are not approved for patients with severe or complicated P. falciparum malaria.

 

CONTRAINDICATIONS:

Artemether & Lumefantrine tablets are contraindicated in persons with a history of hypersensitivity associated with the use of artemether, lumefantrine, or to any of the excipients of Artemether & Lumefantrine tablets.

 

STORAGE:Store in an airtight container, protected from light.

 

PRESENTATION: 1x6 Tablets in one blister in a monopack.

Additional Information:

• Production Capacity: any port in india

Product Details:

Artemether, isolated from Chinese-Vietnamese plant Artemisia annua L., locally called “qinghao”, is used to treat fever and malaria. It is a white crystalline powder with a bitter taste; practically insoluble in water, soluble in chloroform, acetone, and alcohols.

COMPOSITION:

Each ml contains:
Artemether 80 mg
Arachis oil q.s.

INDICATIONS:
Artemether injection is indicated for treatment of severe and complicated malaria caused by P. falciparum both in adults and children in areas where there is multidrug resistance.

CONTRAINDICATIONS:
Artemether is contraindicated in patients with hypersensitivity to artemether or other artemisinin compoundsArtemether is not recommended in the first trimester of pregnancy because of limited data.

STORAGE:In a well-filled container, protected from light.
PRESENTATION:6 Ampoules X 1 ml

Product Details:

Artemether, isolated from Chinese-Vietnamese plant Artemisia annua L., locally called “qinghao”, is used to treat fever and malaria. It is a white crystalline powder with a bitter taste; practically insoluble in water, soluble in chloroform, acetone, and alcohols.

COMPOSITION:
Each ml contains:
Artemether 80 mg
Arachis oil q.s.

INDICATIONS:
Artemether injection is indicated for treatment of severe and complicated malaria caused by P. falciparum both in adults and children in areas where there is multidrug resistance.

CONTRAINDICATIONS:
Artemether is contraindicated in patients with hypersensitivity to artemether or other artemisinin compoundsArtemether is not recommended in the first trimester of pregnancy because of limited data.

STORAGE:In a well-filled container, protected from light.
PRESENTATION:6 Ampoules X 1 ml

Product Details:

We are one of leading manufacturer of Alpha Beta Arteether Injection.

Additional Information:

• Pay Mode Terms: L/C (Letter of Credit),T/T (Bank Transfer)
• Port of Dispatch: Any Port in india

Product Details:

Athemax Arteether Injection is a fast acting blood schizonticidal agent for P. falciparum malaria at the erythrocytic stage. ?-? Arteether is concentrated in parasitized erytrocytes. The functional group responsible for antimalarial activity of Alpha-Beta Arteether is endoperoxide bridge which inhibits the protein synthesis and alters the ribosomal organization and endoplasmic reticulum.

Indications
Severe malaria including cerebral malaria & as a second line drug in chloroquine resistant malaria cases only.

Contraindications
Alpha-Beta Arteether injection is contraindicated in patients hypersensitive to artemisinin derivatives.

Additional Information:

• Pay Mode Terms: L/C (Letter of Credit),T/T (Bank Transfer)
• Port of Dispatch: Any Port in india

Product Details:

Mode of administration
Alpha-Beta Arteether: Injectable.

Mechanism of action
Alpha-Beta Arteether is a fast acting blood schizonticidal agent for P. falciparum malaria at the erythrocytic stage. ?-? Arteether is concentrated in parasitized erytrocytes. The functional group responsible for antimalarial activity of Alpha-Beta Arteether is endoperoxide bridge which inhibits the protein synthesis and alters the ribosomal organization and endoplasmic reticulum.

Indications
Severe malaria including cerebral malaria & as a second line drug in chloroquine resistant malaria cases only.

Contraindications
Alpha-Beta Arteether injection is contraindicated in patients hypersensitive to artemisinin derivatives.

Additional Information:

• Pay Mode Terms: L/C (Letter of Credit),T/T (Bank Transfer)
• Port of Dispatch: Any Port in india

Product Details:

To put into action our exclusive market and business plannings, we are readily engaged as manufacturer, supplier and exporter of Artemether Lumefantrine Tablets in Ahmedabad, Gujarat, India.

• Brand Names: Tiotem
• Generic Name: artemether/lumefantrine (ar-TEM-e-ther/LOO-me-FAN-treen)
• Tiotem is used for: Treating certain types of malaria in adults and children who weigh at least 11 pounds (5 kg). It may also be used for other conditions as determined by your doctor.
• Tiotem is an antimalarial agent.

Additional Information:

• Pay Mode Terms: L/C (Letter of Credit),T/T (Bank Transfer)
• Port of Dispatch: Any Port in india

Product Details:

Mode of administration
Alpha-Beta Arteether: Injectable.

Mechanism of action
Alpha-Beta Arteether is a fast acting blood schizonticidal agent for P. falciparum malaria at the erythrocytic stage. ?-? Arteether is concentrated in parasitized erytrocytes. The functional group responsible for antimalarial activity of Alpha-Beta Arteether is endoperoxide bridge which inhibits the protein synthesis and alters the ribosomal organization and endoplasmic reticulum.

Indications
Severe malaria including cerebral malaria & as a second line drug in chloroquine resistant malaria cases only.

Contraindications
Alpha-Beta Arteether injection is contraindicated in patients hypersensitive to artemisinin derivatives.

Additional Information:

• Pay Mode Terms: L/C (Letter of Credit),T/T (Bank Transfer)
• Port of Dispatch: Any Port in india

Product Details:

• Each 2 ml contains
• Composition:
• α / β arteether 150mg
• Arachis oil q.s.

We are identified as one of the major a/b arteether injection manufactures in India.The Antimalarial injection offered by us is extensively demanded in the market due to the fast & effective relief from the respective eliments. The antimalarial Alfa-Beta arteether injection is hygienically packed to

Function:
prevent contact from external contaminents. Severe malaria including cerebral malaria and as a second line drug in chloroquine resistant malaria cases only.

• Dosage & Administration : α / β arteether is for intramuscular use only.
• Adult : 150mg i.e. 1 ampoule of b arteether once daily for 3 consecutive days.
• Children : 3mg/Kg per day administered by intramuscular injection over a 3-day period.

The injection must be given under aseptic conditions, deep intramuscularly in the upper lateral quadrant of the buttock. No other drug should be mixed in the same syringe.

• Available in : 2 ml. Ampoule

Product Details:

Antimalarials are drugs which are used for prophylaxis, treatment & prevention of Malaria. They are used for treatment of Malaria in individuals with suspected or confirmed infection and for prevention of infection in individuals visiting a malaria-endemic region who have no immunity (prophylaxis).
Dihydroartemisinin + Piperaquine Phosphate Oral Suspension is an oral fixed-dose artemisinin-based Combination antimalarial and antiprotozoal agent. This combination therapy is used for treatment of all forms of malaria, including those caused by multi drug-resistant strains. Dihydroartemisinin + Piperaquine Phosphate is indicated for the treatment of various types of malaria including chloroquine-resistant P. falciparum and P.

Additional Information:

• Port of Dispatch: Any Port in india

Product Details:

QUININE DIHYDROCHLORIDE INJECTION BP 600MG/2ML

Quinine acts primarily as a schizontocide ie it suppresses the asexual cycle of development of malaria parasites in the erythrocytes. It has little effect on sporozoites or pre-erythrocytic forms of malarial parasites. It does not, therefore, prevent the relapse of Plasmodium vivax infections.

Quinine is also gametocidal for P. vivax and P. malariae but not for P. falciparum, and therefore does not prevent transmission of this infection by the mosquito.

Plasma concentrations of quinine between 8 and 15mg/litre are effective clinically and are generally non-toxic; such values are usually achieved with the standard therapeutic dose.

Approximately 70% of quinine is bound to proteins in the plasma in healthy subjects, rising to about 90% in patients with malaria. The concentration in cerebrospinal fluid is about 2-5% of that in the plasma. Quinine is extensively metabolized, especially in the liver, and excreted in the urine. Estimates of the proportion of unchanged quinine excreted in the urine vary from less than 5% to 20%.

The metabolites are excreted in the urine; renal excretion of quinine is twice as rapid when the urine is acidic as when it is alkaline.

The elimination half-life in healthy subjects is about eleven hours, but may be prolonged in patients with malaria.
The pharmacokinetics of quinine may be altered significantly by malaria infection, with reductions in both clearance and the apparent volume of distribution.

Quinine crosses the placenta and is excreted in breast milk.

Additional Information:

• Pay Mode Terms: L/C (Letter of Credit),T/T (Bank Transfer)
• Port of Dispatch: Any Port in india

Product Details:

INDICATIONS: For the treatment of acute attacks of malaria, including attacks due to strains of Plasmodium falciparum resistant to chloroquine or resistant to multiple drugs. Quinine is used parenterally for cerebral malaria, severe or complicated, or when Vomitosevitan retention of a drug administered orally. Quinine dihydrochloride is the salt that is generally used for the preparation of injections.

Additional Information:

• Production Capacity: any port in india