Antipyretics, NSAIDS & Pain Management

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Pharmacology is a crucial part of medicine wherein various drugs are used to advance the well-being of an individual. Some drugs cure the infection or a disease; few prevent the occurrence of a symptom or a disease, and few are used in long-term treatment of the disease. Drugs are obtained from the plants as well as they can be synthesized organically. The drugs are used in various combinations or a single drug by the pharmaceutical industry during its preparation. The half-life of each drug is different, and the dosage of the drug depends on the half-life of the drug. The below information gives the detailed description of Dicyclomine 20MG + PARACETAMOL 500MG TABLET drug.

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Diclofenac injection is a nonsteroidal anti-inflammatory drug (NSAID) used to treat adults with mild to moderate pain. It is used alone or given with other opioid (narcotic) pain medicines to treat adults with moderate to severe pain.

This medicine is to be given only by or under the direct supervision of your doctor.

This product is available in the following dosage forms:

• Solution

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We are one of the leading manufacturers and exporters of Anti Inflammatory Tablets.

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We have emerged as one of the leading manufactureres in offering Anti Inflammatory Drugs. (Only For Export)

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Febuxostat is a xanthine oxidase inhibitor used for treating gout caused by excessive levels of uric acid in the blood (hyperuricemia). Febuxostat Uric acid is formed from the breakdown of certain chemicals (purines) in the body. Hyperuricemia occurs when the body produces more uric acid than it can eliminate.

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Aceclofenac 100 MG Tablet is a non-steroidal anti-inflammatory drugs (NSAIDs), prescribed for people with painful rheumatic conditions such as osteoarthritis, rheumatoid arthritis and ankylosing spondylitis. Aceclofenac 100 MG Tablet works by blocking the effect of cyclo-oxygenase (COX) enzymes which make chemical prostaglandins at sites of injury or damage, causingpain,swellingand inflammation. It eases pain and reduces inflammation. This medicine should not be given duringpregnancyor to mothers that are breastfeeding. Is not recommended for children. This drug is available in tablet form and is taken orally.

Aceclofenac 100 MG Tablet has side effects includingdiarrhoea,stomach pain,nausea, constipation,vomiting, skinrashesetc. If the side effects are severe or persistent it is advisable to consult your doctor.

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Uses

Diclofenac is used to relieve pain, swelling (inflammation), and joint stiffness caused byarthritis. Reducing these symptoms helps you do more of your normal daily activities. This medication is known as a nonsteroidal anti-inflammatory drug (NSAID).

If you are treating a chronic condition such as arthritis, ask your doctor about non-drug treatments and/or using other medications to treat your pain. See also Warning section.

OTHER USES: This section contains uses of this drug that are not listed in the approved professional labeling for the drug but that may be prescribed by your health care professional. Use this drug for a condition that is listed in this section only if it has been so prescribed by your health care professional.

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Diclofenac is a nonsteroidal anti-inflammatory drug (NSAID) used to treat mild-to-moderate pain, and helps to relieve symptoms of arthritis (eg, osteoarthritis or rheumatoid arthritis), such as inflammation, swelling, stiffness, and joint pain. This medicine does not cure arthritis and will only help you as long as you continue to take it.

This medicine is also used to treat ankylosing spondylitis, which is a type of arthritis that affects the joints in the spine, and other painful conditions such as menstrual cramps.

Diclofenac is also used to treat acute migraine attacks, with or without aura, in adults. It will not prevent or lessen the number of migraine attacks.

This medicine is available only with your doctor’s prescription.

This product is available in the following dosage forms:

• Capsule
• Powder for Solution
• Capsule, Liquid Filled
• Tablet
• Tablet, Enteric Coated
• Tablet, Extended Release

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Diclofenac Potassium Serratiopeptidase Tablets

Diclofenac Potassium is a non-steroidal anti-inflammatory agent (NSAIDs) with antipyretic and analgesic actions.
Serratiopeptidase is a proteolytic enzyme (protease) produced by enterobacterium Serratia sp. E-15 used in the prevention of pain and swelling.


Indications and Usage:

•  For the treatment of primary dysmenorrhea.
•  For the treatment of mild to moderate pain.
•  For the relief from the signs and symptoms of osteoarthritis.
•  For the relief from the signs and symptoms of rheumatoid arthritis.
•  Chronic inflammation.
•  Headaches, muscle and joint pain.
•  Serious diseases like cancer and heart disease.
•  Superficial thrombophlebitis.
•  Postoperative & traumatic swelling.
•  Acute or chronic ear, nose or throat disorder.
•  Rationale of Combination:

Product Description:
Diclofenac Potassium is used as an anti-inflammatory agent to pacify mild to moderate pain and inflammation. Common conditions associated with pain and
inflammation include arthritis, trauma, surgery and fibermyalgia. Additionally, serratiopeptidase helps to reduce fluid retention in affected areas, which
contributes to proper drainage and a quicker recovery.


Pharmacology:
Diclofenac Potassium:
Diclofenac Potassium is an acetic acid non-steroidal anti-inflammatory drug (NSAIDs) with analgesic and antipyretic properties. Diclofenac Potassium inhibits the
production of prostaglandins by inhibiting COX-1 and COX-2 pathways thereby exhibiting anti- inflammatory effects.
Pharmacokinetic:
Absorption: Well absorbed following oral administration.
Distribution: widely distributed in animals. Plasma protein binding exhibited is >99%.
Elimination: hepatic metabolism leads to elimination through urine.
Serratiopeptidase:
Serratiopeptidase is an enzyme isolated from a non-pathogenic bacteria called enterobacteria Serratia E15. Serratiopeptidase has powerful anti-inflammatory
properties and is particularly useful for post-traumatic swelling, fibrocystic breast disease and bronchitis. It is able to digest dead tissue, blood clots, cysts, and
arterial plaques.
Pharmacokinetic:



Absorption: On oral administration, serratiopeptidase is absorbed in GI tract.
Distribution: Distributed throughout the body tissues, unchanged via systemic circulation. It reaches in higher concentration in inflamed tissues.
Serratiopeptidase levels in inflammatory exudates rises gradually with decline in blood levels indicating that serratiopeptidase is quite rapidly transferred to the
site of inflammation.
Adverse Effects:
? Skin rash
? Diarrhea
? Gastrointestinal disturbance
? Noseblee
? Dizziness
Contraindications:
Diclofenac sodium + Serratiopeptidase is contraindicated in patients with active GI bleeding or perforations, asthma, renal or hepatic disorders, hypertension,
porphyria, peri-operative pain in CABG surgery patients and bleeding disorders.


Drug Interactions:
Diclofenac potassium+ Serratiopeptidase should not be taken concomitantly with other NSAIDs, anticoagulants including low-dose/LMW heparin, sucralfate,
triamterene, cyclosporine, cholestyramine, colestipol, digoxin, aspirin, methotrexate and lithium.


Other Interactions:
Diclofenac potassium + Serratiopeptidase should be taken with food. Take the drug immediately after meals to avoid GI disturbances.
Storage
Store at 15-30°C.

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Description:

This tablet is used for Acute migraine attacks, Analgesic, Treatment for intractable nausea and vomiting, Antipyretic, Abdominal cramps, Osteoarthritis, Treatment for symptoms associated with idiopathic or diabetic gastro paresis, Rheumatoid arthritis, Gas, Juvenile idiopathic arthritis and other conditions. Tablet may also be used for purposes not listed in this medication guide.

Tablet contains Domperidone and Naproxen as active ingredients.

Tablet works by blocking the dopamine receptors; blocking the effect of enzyme called cyclooxygenase resulting in decreased production of prostaglandins.

Compositions:

Tablet is composed of the following active ingredients (salts)

NAPROXEN 500 MG 

DOMPERIDONE 10 MG 

Interactions:

If you use other drugs or over the counter products at the same time, the effects of Tablet may change. This may increase your risk for side-effects or cause your drug not to work properly. Tell your doctor about all the drugs, vitamins, and herbal supplements you are using, so that you doctor can help you prevent or manage drug interactions. Tablet may interact with the following drugs and products:

· Aluminium hydroxide and oxide

· Amiodarone

· Amprenavir

· Antacids

· Aprepitant

· Atazanavir

· Atropine

· Bisoprolol

· Ciprofloxacin

· Clarithromycin

 

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• Production Capacity: any port in india

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Our rich industry expertise in this domain has enabled us to offer Deflazacort Tablets which is used in situations where treatment is necessary; the offered tablets are processed with finest quality ingredients and with the aid of latest formulation techniques at our highly equipped labs. These tablets effectively serve the various medical purposes and broadly demanded in medical sector.

Features:

• Accurate pH value
• Fast result
• Free from harmful chemicals

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